Zyloric contain Allopurinol as active ingredient in addition to excipients like lactose monohydrate, corn starch, povidone K90 and magnesium stearate. Zyloric tablets should be taken only on prescription of the doctor
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Zyloric lowers uric acid into blood and urine. It is used in gout, ie in deposits of uric acid crystals in the skin, joints and kidneys, as well as in other diseases that cause a therapy-requiring increase in the concentration of uric acid in the blood.
The usual dosage is 100 – 300 mg Zyloric daily; In severe cases, the doctor may increase the dose to 900 mg.
The dose 100 – 300 mg daily (1 tablet of 100 mg or 300 mg) is taken as a single dose after a meal with enough liquid. If the dosage is higher, follow the instructions of the doctor.
How to take Zyloric?
If you have forgotten to take the daily tablet, continue with the regular intake. The remaining tablet then take at the end.
Do not change the prescribed dosage on your own. If you think the medicine is too weak or too strong, talk to your doctor or pharmacist.
It often causes skin symptoms such as redness, blisters or dandruff.
The following side effects may occur when taking Zyloric in rare cases:
- Fever and chills, headache, muscle aches (flu-like symptoms) and general malaise.
- Schwerwiegende changes on the skin, for example, inflammation of the mouth, in the throat, on the nose, on the genitals and conjunctivitis (red and swollen eyes), large-scale bladder and dandruff.
- Severe hypersensitivity reactions with fever, rash, joint pain and changes in blood count and liver function (these may be signs of multiorgan hypersensitivity disease).
If skin problems occur, stop taking Zyloric and inform your doctor immediately.
Nausea and vomiting can be avoided by always taking Zyloric after a meal.
Zyloric shouldn’t be taken in case of known hypersensitivity to Allopurinol or an excipient of Zyloric.
It should be avoided in cases of;
- Stevens- Johnson syndrome
- Toxic Epidermal Necrolysis
- Wilson’s disease
- Fanconi syndrome
High levels of uric acid in the blood are due to a metabolic disorder that can be triggered by various factors, such as overeating. It is therefore important to pay attention to an ideal weight and a mixed, varied diet. To avoid are alcohol and offal. When kidney stones is to pay attention to a large amount of drinking.
When should I be careful when taking Zyloric?
- In the case of known, severe kidney and / or liver disease, special care should be taken when using the device and special supervision by the doctor is required to find the most appropriate dosage.
- Severe skin rashes (hypersensitivity syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis) have been reported with the use of allopurinol. The rashes are often accompanied by inflammation in the mouth, throat, nose, genitals and conjunctivitis (red and swollen eyes). These serious rashes are often preceded by flu-like symptoms such as fever, headache and body aches. The rash can spread to large blistering and skin flaking.
- The concomitant use of hypertensives (ACE inhibitors) or diuretics (especially thiazides) increases the risk of a hypersensitivity reaction, especially if there is additional renal impairment.
- There is a specific genome (the so-called HLA-B * 5801) in which the risk of severe skin reactions is significantly increased. This genome is particularly prevalent in some Han Chinese, Indian, Thai and African populations.
- Severe skin reactions may therefore occur more frequently in people of Han Chinese, Indian, Thai or African descent.
- If skin problems occur, stop taking Zyloric and inform your doctor immediately.
- At the beginning of the treatment, an acute attack of gout may occur. If you experience any symptoms (severe painful, red, swollen and overheated joint), please contact your doctor.
- If treatment is started during an acute attack of gout, further attacks can be triggered. If you have acute attacks of gout before starting treatment, you should therefore inform your doctor. The doctor then decides when to start the treatment.
- Few patients have been reported to have dizziness while on Zyloric, which may affect their ability to react, drive and use machines!
Tell your doctor or pharmacist or your pharmacist if you:
- Suffering from other diseases,
- Have allergies
- Take other medicines (also self-bought!) or use externally.
Pregnancy & Breastfeeding
Can Zyloric be taken during pregnancy ? the answer is that If you are pregnant, would like to become pregnant or breastfeed, Zyloric should only be taken on the express prescription of the doctor.
The Zyloric tablets are usually packaged in 14-day strips but may be available in other packs like;
- Zyloric 100 mg: 100 tablets
- Zyloric 300 mg: 28 and 84 tablets