Nexium review

Nexium is used to treat heartburn, acid indigestion, sour stomach, and other conditions in which your stomach makes too much acid. Esomeprazole also is used in combination with antibiotics to treat ulcers.

How Drug Works

This medicine works by decreasing the amount acid made by your stomach to treat acid reflux for example.

How Taken

Esomeprazole is available in a delayed-release capsule and should be swallowed whole, not crushed, or chewed. The best time to take this medicine is at least 1 hour before a meal. If you cannot swallow the capsule, add one tablespoon of cool, soft applesauce to an empty bowl, open one esomeprazole capsule, and carefully sprinkle the pellets onto the applesauce. Mix the pellets with the applesauce and swallow the entire tablespoon immediately. Do not chew the pellets in the applesauce and do not save the pellets and applesauce for another dose.

Possible Side Effects

Tell your doctor if any of these symptoms are severe or do not go away: stomach pain constipation dry mouth change in taste headache diarrhea upset stomach gas


If your symptoms do not improve, or get worse, while taking this medicine, call your doctor. Tell your doctor and pharmacist if you are allergic to esomeprazole, omeprazole (Prilosec), lansoprazole (Prevacid), or any other drugs. Tell your doctor if you have ever had liver disease. Do NOT stop taking esomeprazole without talking to your doctor.

Drug Interactions

Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially iron supplements or vitamins that contain iron, ketoconazole (Nizoral), digoxin (Lanoxin), and herbal products.


There have not been well-controlled studies using esomeprazole during pregnancy. Use only if clearly needed and if the benefit outweighs any potential risk. For nursing mothers, it is likely that esomeprazole is excreted in breast milk, so caution should be used in deciding whether to discontinue the drug or the breast-feeding.

More Information

Nutrient depletions with this medication include Vitamin B-12, so ask your doctor about possible supplementation. Some foods and beverages can make your symptoms worse. Your doctor can tell you which foods you should avoid or eat only in small quantities.

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