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Haldol review – Antipsychotic with Serious Side Effects

Haldol belongs to the group of drugs called neuroleptics. Haldol should only be used on prescription of the doctor.

Haldol is marketed under different brand and generic names like : Serenase, Aloperidolo, Serenace tablets, Norodol, Aloperidin, Novo-Peridol, Peridol, Haloxen Tablet, Halozen, haridol and Sevium.

Haldol Uses

Haldol is used in disorders of thinking, feeling or acting such as: delusions, unusual mistrust, hallucinations (hearing something in another way, seeing or feeling what is not there); Confusion; strong arousal states.

In addition, Haldol is sometimes used in uncontrolled movements such as tics, which are associated with significant impairment, as well as nausea and vomiting, when the usual medicines do not work against these symptoms.

When should Haldol not be used?

  1. In case of hypersensitivity to haloperidol (active substance) or any of the excipients contained in Haldol.
  2. In children under 3 years.
  3. If you have Parkinson’s disease or have suffered earlier.
  4. After taking alcohol or medicines that have a depressant effect on the nervous system.

Haldol Ingredients

  • 1 tablet Haldol at 1 mg contains as active ingredient 1 mg haloperidol, lactose monohydrate, hardened cottonseed oil (made from genetically modified cottonseed) and other excipients.
  • 1 tablet Haldol at 10 mg contains as active ingredient 10 mg haloperidol, dye: quinoline yellow (E104) and other excipients.
  • 1 ml Haldol drops 2 mg / ml contain as active ingredient 2 mg haloperidol, preservative: methylparaben (E 218) and other excipients. 1 ml = 20 drops.

Cautions when taking Haldol

If you suffer from or have suffered from any of the following conditions, you should tell your doctor, as he or she may wish to monitor closely or prescribe other medicines: heart disease; Cerebral hemorrhage, risk of a stroke; Depressions; Liver problems; Epilepsy or other conditions that can cause seizures (for example, during an alcohol withdrawal course) or hyperthyroidism (blood clots or clots in the family history). Blood clots in the lungs and legs were seen in patients taking antipsychotic drugs.

Do not drink alcohol during Haldol therapy as Haldol increases the effect of the alcohol.

There may be interactions between Haldol and the following medicines: medicines that slow down your reactions, such as sleeping pills, sedatives, some strong painkillers; Medicines for depression; Medicines for hypertension, medicines for epilepsy.

Therefore, tell your doctor if you are taking any of these or any other medicines, he or she will decide which medicines you can take with Haldol.

Haldol may cause drowsiness and may affect the ability to react, drive and use tools or machines. In addition, Haldol can cause movement disorders. Do not operate machinery or drive a vehicle until your doctor has advised you how to react to the medicine.

Tell your doctor, pharmacist or pharmacist if you have other illnesses, allergies or are taking or externally using other medicines (including self-bought ones!).

Pregnancy & Breastfeeding

If you are pregnant, or you want to get pregnant, you should not take Haldol unless your doctor tells you to. When Haldol is used during the last trimester of pregnancy, newborn babies may experience tremors, muscle stiffness, weakness, drowsiness, agitation, difficulty breathing or feeding problems.

Please inform your doctor immediately in case of pregnancy in order to discuss the further procedure. The treatment should under no circumstances be discontinued at its own discretion. Sudden discontinuation of Haldol can have serious consequences.

Please inform your gynecologist or obstetrician immediately about taking it during pregnancy, especially if there are described abnormalities in your child after the birth.

Since Haldol passes into breast milk, the medicine must not be taken during breast-feeding or it should be weaned.

How to use Haldol?

Haldol is available in the form of tablets and drops. You can take Haldol during or between meals. The tablet should be swallowed with a little water. Add the drops in a little water or fruit juice and drink the liquid.

The doctor will change the dose until the best amount is found. Your doctor will tell you exactly how many tablets or what number resp. how many milliliters (ml) of drops do you need. In general, treatment is started with a low dose and increased to the expected effect. It is important that you adhere strictly to the prescribed dosage.


It may take some time before the full effect of Haldol occurs. Stop the therapy only if the doctor allows it. If you stop therapy too soon, without the consent of your doctor, your problem may return. If your doctor instructs you to discontinue the therapy, you must take care of his resp. follow their instructions, otherwise, for example, nausea and vomiting may occur.

Do not change the prescribed dosage on your own. If you think the medicine is too weak or too strong, talk to your doctor, pharmacist or pharmacist.

Instructions for opening the glass bottle and for using the dosing pipette:
Instructions for opening the 100 ml bottle (100 ml drops at 2 mg / ml) and handling the dosing pipettes

Fig. 1: The bottle has a child-resistant closure and is opened as follows:

Press the plastic cap down while turning it counterclockwise.

Remove plastic cap.

Make sure that the piston in the dosing pipette is at the very bottom (push down the upper pipette ring as far as possible).

Fig. 2: Insert plastic pipette into the bottle. Hold the bottom ring with one hand and pull the top of the pipette with the other hand until the desired mark in milliliters (ml) appears on the pipette piston, exactly at the level of the lower pipette ring.

Fig. 3: Carefully pull the pipette on the lower ring out of the bottle.

Empty the pipette contents into a glass of water or fruit juice by pressing the top pipette ring all the way down. Close the bottle with the plastic cap again. After each use, clean the dosing pipette thoroughly by pulling the piston out of the cylinder and rinsing both parts under running water. Reassemble the dosing pipette after drying, allow to dry and store in a clean place.

Instructions for opening the plastic bottle:

The plastic bottle of Haldol 2 mg / ml drop 1 × 30 ml is provided with a child-resistant cap and must be opened as follows: Push the cap downwards while turning it counterclockwise. After removing the cap, you can count the appropriate number of drops and take with a little liquid.

Haldol Side Effects

The following side effects may occur during treatment with Haldol:

Very often:

  • Excitement.
  • Entry and sleep through problems.
  • Coordination disorders or involuntary muscle movements (also known as “extrapyramidal symptoms”). These may include: slow, stiff or jerky movements of the limbs, neck, face, eyes or mouth and tongue. This can lead to an unusual and involuntary posture or facial expression.
  • Abnormally excessive movements of the body or limbs.
  • A headache.


  • Sad or depressed mood.
  • Psychotic disorders (such as delusions, unusual mistrust, hallucinations)
  • After prolonged treatment, twitching of the tongue, face, mouth, or jaw, and possibly with slow, worm-like movements of the tongue and mouth, and possibly also with limited ability to fully open the mouth, all of which may not disappear even upon discontinuation of treatment.
  • Coordination disorders and involuntary muscle movements such as: Spastic movement of the eyeballs in a rigid position, usually upwards; Slowing down the movement process; jerky movements, trembling, muscle stiffness, muscle contractions associated with twitching and stereotyped movements or abnormal postures, expressionless face; abnormal gait, inability to sit still.
  • High blood pressure.
  • Dizziness.
  • Excessive drowsiness.
  • Dizziness.
  • Vision problems.
  • Abnormally low blood pressure (so-called hypotension); abnormally low blood pressure when getting up or changing position.
  • Constipation, dry mouth, increased salivation, nausea, vomiting.
  • Skin rash.
  • Inability to let water.
  • Impotence or erectile dysfunction.
  • Unintentional weight gain or loss.


  • Allergic reactions, such as hives or facial swelling.
  • Confusion.
  • decreased sex drive or libido.
  • Loss of appetite.
  • Heartburn.
  • Restlessness.
  • Cramps.
  • Symptoms as in Parkinson’s disease.
  • Sedentary lifestyle.
  • Jerky yielding of a passively moved limb (gear phenomenon).
  • Sedation.
  • Involuntary muscle contractions.
  • See blurry.
  • Abnormally accelerated heartbeat.
  • Difficulty breathing (shortness of breath). Liver inflammation (so-called hepatitis); Too much bile in the blood with accompanying yellowing of the skin, gums and eyes (so-called jaundice).
  • Excessive photosensitivity of the skin. Itching on the skin.
  • heavy sweating.
  • Menstrual disorders such as menstrual pain and / or absence of menstruation.
  • Leakage of fluid from the nipples, breast sensitivity or pain.
  • Gait disturbance.
  • Abnormal increase in body temperature.
  • Swelling of the limbs due to excessive water retention.


Milk formation in the breast.
Malignant neuroleptic syndrome (a medical emergency involving stiffening of the body and high fever). In this case, you must immediately contact your doctor resp. Contact the doctor.
Sideways movement of the eyes in conjunction with the feeling that the room is turning.
Narrowing of the trachea accompanied by whistling breath sounds.
Excessively heavy menstrual bleeding.
Disorder of sexual function.

Very rare:

  • The blood cells responsible for the defense against infection and blood coagulation (white blood cells or platelets) can fall sharply in numbers.
  • severe allergic reaction, which may be associated with: Swelling of the face, lips, mouth, tongue and throat,
    Swallowing and breathing difficulties, itchy rashes (urticaria).
  • Disruption of water excretion via the urine. As a consequence, liquid deposits can occur.
  • Abnormally low blood sugar levels.
  • Additional heartbeats; rapid, yet coordinated contractions of the heart; fast, no longer coordinated contractions of the heart muscle, which can quickly lead to death without treatment.
    Swelling of the vocal cords and the larynx due to fluid retention, spasms of the vocal cords and larynx.
  • Failure of liver function.
  • Small purplish spots on the skin or other tissues caused by inflammation of the blood vessels, sometimes together with pain-sensitive nodules; a skin rash associated with peeling of the upper skin layer.
  • Decay of muscle tissue (called rhabdomyolysis)
  • Enlargement of the breast, even in men.
  • Abnormally prolonged erection that is not based on sexual arousal.
  • Facial swelling due to heavy fluid retention.
  • Abnormally low body temperature.
  • When Haldol is used during the last trimester of pregnancy, newborn babies may experience tremors, muscle stiffness, weakness, drowsiness, agitation, difficulty breathing or feeding problems.

If you experience high fever, muscle stiffness, rapid breathing, abnormal sweating, or decreased alertness (loss of consciousness), you should tell your doctor immediately. It may be that your body is not responding properly to the medicine.

Other important information : Elderly patients with dementia who require treatment with Haldol due to behavioral problems may be at increased risk of dying from untreated patients.

What should also be noted?

Haldol tablets and drops should be stored in the original sealed package (protected from light) at room temperature (15-25 ° C) and out of the reach of children.

The medicine should only be used up to the date marked on the container with “Exp”.

Further information can be obtained from your doctor, pharmacist or doctor. These people have the detailed information for specialists.

Which packs are available?

  • Haldol 1 mg tablets: packs of 50 tablets.
  • Haldol 10 mg tablets: packs of 20 tablets.
  • HALDOL Injection.
  • Haldol 2 mg / ml drops: packs of 30 ml (plastic bottle) and 100 ml (glass bottle).

The drops of the 30 ml Haldol 2 mg / ml pack are packed in a plastic bottle with a dropper. The remaining drops are available in a glass bottle, which is supplied with a separate dosing pipette (Haldol 2 mg / ml, pack of 100 ml) for the correct removal of the drops.

Haldol Overall Rating

Ease of Use
Action Duration
Side Effects Tolerability


Haldol should only be used on prescription of the doctor.

User Rating: 3.62 ( 3 votes)
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